Diagnostic delays in measles cases may fuel resurgence, study finds
A recent analysis of medical records reveals that approximately 7 percent of confirmed measles cases in the United States experience at least one misdiagnosis within the two weeks leading up to a correct diagnosis. The study, conducted by researchers at the University of Iowa and examining data from 4,651 cases reported between 2001 and 2023, identified 381 instances of misdiagnosis.
These diagnostic delays, described as “not uncommon,” are raising concerns about the potential for increased transmission of the highly contagious virus, particularly in outpatient clinics and hospital waiting areas. Researchers found that 81 percent of these delays occurred in outpatient settings, highlighting the risk of airborne spread.
The study also pointed to factors contributing to misdiagnosis, including the prescription of respiratory antibiotics and challenges in obtaining accurate symptom descriptions from children under the age of two. Doctors unfamiliar with measles, which was previously eliminated in the U.S. in 2000, may not initially consider it as a possible diagnosis.
Measles cases are currently spreading in Pennsylvania, Wisconsin, and Florida. As of this year, there have been 4,852 confirmed cases nationwide, with Pennsylvania reporting 1,433 cases as of Monday, a significant increase from the 2,289 cases recorded in 2025. These outbreaks are largely linked to communities with lower vaccination rates, and all reported deaths have occurred in unvaccinated individuals.
Two doses of the measles, mumps, and rubella (MMR) vaccine are highly effective, with a 97 percent success rate against infection and providing lifelong protection. Without vaccination, measles can lead to serious complications such as brain swelling, pneumonia, and ear infections.
However, vaccination rates are declining. Data from both state and federal sources indicate a decrease in MMR vaccine coverage among kindergarten-aged children between the 2024-2025 and 2025-2026 school years. Idaho experienced the most significant drop, falling over 3 percentage points (from 78.5 percent to 75.2 percent), while Louisiana and Virginia saw declines of approximately 2 percentage points.
Source
“New study finds a high number of measles cases are misdiagnosed”
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